P374 Probiotics can extend remission of ulcerative colitis

Probiotics and remission of ulcerative colitis: a systematic review.

BACKGROUND Ulcerative colitis (UC) is an acute and inflammatory disease of the large bowel of unknown aetiology. The use of probiotics for this disease remains controversial. The objective of this systematic review was to identify studies based on randomised controlled trials comparing the effect of probiotics to the effect of anti-inflammatory drugs or placebo in the remission of UC. METHODS...

Review article: defining remission in ulcerative colitis.

BACKGROUND There is no international agreement on scoring systems used to measure disease activity in ulcerative colitis, nor is there a validated definition for disease remission. AIM To review the principles and components for defining remission in ulcerative colitis and propose a definition that will help improve patient outcomes. METHODS A review of current standards of remission from t...

Upregulation of GRAIL is associated with remission of ulcerative colitis.

Abrogating tolerance against unidentified antigens is a critical step in the pathogenesis of ulcerative colitis (UC). T cell anergy, one of the main mechanisms of tolerance, has been shown to be induced by E3 ubiquitin ligases, such as gene related to anergy in lymphocytes (GRAIL), Itch, and c-Cbl in mice. However, it is not well known whether these E3 ligases play roles in human diseases. The ...

Central retinal vein occlusion during remission of ulcerative colitis.

BACKGROUND Retinal vascular disease is a rare complication of ulcerative colitis. CASE We report a patient who developed unilateral nonischemic central retinal vein occlusion (CRVO) (papillophlebitis) without any other retinal vascular disease during remission of ulcerative colitis. OBSERVATIONS The best-corrected visual acuities were 1.5 OD and 0.7 OS. Dilated and tortuous retinal veins an...

ulcerative colitis remission after renal transplantation: two case reports